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Location: Minneapolis, Minnesota, United States

Diagnosed with Type 1 diabetes in April of 1980. I recognize the incredible mental struggle of living with diabetes. I hope to share my struggles, my successes, and everything in between.

Monday, June 11, 2007

Weight Loss & Symlin for the Non-Diabetic Crowd?

I stumbled on an interesting article by Rigel Gregg over at Thatsfit.com this weekend which highlighted an article on WebMD.com; "Fullness Hormone May Boost Weight Loss".

This article talks about a study published online in the American Journal of Physiology - Endocrinology and Metabolism, that focuses on the use of Symlin to help obese participants feel full and eat less.

I guess it's an interesting thought. But don't people without diabetes already produce this hormone?

Seems to me (based on NO medical or scientific knowledge or background on my part) that messing around with an already functional hormonal system may not be the best thing to do.

But what do I know?

21 Comments:

Blogger Scott said...

You're right, and the long-term consequences of hormone supplementation may be detrimental, but the basic idea seems to be that the need for weight loss trumps everything. Who knows if that's the right answer!

10:18 AM  
Blogger Vivian said...

I know a non diabetic person who was using Byetta for a while, don't think she ever took Symlin though. She has PCOS, is obese and is at high risk for Type 2 diabetes. The Byetta was seriously helping her on all fronts until the insurance would not cover it because she was not officially a diabetic. I wonder if she had been allowed to stay on it if it would have prevented much of what seems sure to happen in her health. I know her reasoning with the weight loss was that with PCOS the symptoms can't be managed well without weight loss but you can't lose the weight because of the PCOS. It just becomes a cycle that seems impossible to break. I just hope that when people use meds as they were not intended that they are careful and informed.

10:42 AM  
Blogger Zazzy said...

One of the theories of obesity is that either the person doesn't produce amylin or isn't sensitive to it, essentially causing the body to not recognize "full" until it's overfull. I can relate to that but I don't know whether it's a chemical problem or I've just lost my awareness of "full."

11:55 AM  
Blogger Nicole P said...

My doctor put me on Symlin to boost weight loss. I didn't have post-prandial highs... It worked, I lost 15 lbs in less than 3 weeks. Of course - I also dealt with bad hypos and wasn't eating much of anything...

11:59 AM  
Blogger Kendra said...

That's interesting...I guess it's possible that people with weight problems are not producing hormones / using their hormones correctly (amylin and insulin included).

I think it's very interesting that Symlin is so highly touted in weight loss circles - even among Type I diabetics. I've actually had T1 diabetics act like the blood sugar effects are secondary to the weight loss in their eyes. I'd just use it for the post prandial spiking as that's what I thought it was initially developed for. Guess this is an unexpected bonus!

2:33 PM  
Blogger hl said...

I used Byetta for about six months as my insulin intake started creeping upward as well as my weight. It was great as I lost the 20 lbs and kept them off. I then went on the pump and used Symlin for two months which did cut down on boluses but seemed to be more trouble and really didn't curtail my food intake as Byetta did...so I'm off of it now...my endo has suggested tyring Byetta again but I'm thinking not at the present time...I want to be free of injections for awhile.

11:14 PM  
Anonymous Sue said...

Thanks for this informative blog and comments

1:08 AM  
Anonymous Anonymous said...

It's good to know there are individuals out there who can relate to the topic of type 1 diabetes. I have been diagnosed as a type 1 for five years...still not quite suffice with the whole experience! My doc recently prescribed me to Symlin. I've only been on it for one week and have not had the "nausea, tiredness" side-effects. I don't know when you're supposed to see some sort of weight loss result? I'm sure it's quite different for certain individuals.

I recently read an article in the magazine, "Diabetes Forecast" (Aug 07 edition)[Mail Call] about Weight Management using Symlin and/or Byetta. Do you actually lose weight? Or is this particular drug just some sort of hype?

5:24 PM  
Blogger Scott K. Johnson said...

Thanks for stopping by anonymous - sorry for my delay in replying.

I don't know from personal experience, but one of the things Symlin is supposed to do is to help you feel full and more satisfied faster. With that in mind I do think that some users don't eat as much, and therefore do lose some weight.

I also have read a user experience from David Mendosa that he has experienced a fair amount of weight loss using Byetta. I don't think it's hype, but like everything else with diabetes, what works for one doesn't always work for another.

Please do keep us posted on how things are going for you.

Thanks!

9:25 PM  
Anonymous joy said...

I ran across your blog and became interested because of the medication for the diabetes. I have a program for weight loss (NOT a diet) the focuses on behaviour modification and nutritional counseling and hypnotherapy. I was wondering if I worked with your doctor if that would be successful? I was curious. I would love to help you.
Joy with the Hungry Heart.

2:11 AM  
Blogger kevin said...

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5:00 AM  
Blogger luccy said...

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12:52 AM  
Anonymous Anonymous said...

I am on Byetta right now to falciliate weightloss I am not overweight. I am about 145 lbs and 5' 6" I think I'm considered heavy but I used to be a weight lifter. I've been on it for a month and two weeks and I've lost about 8 pounds. The 10 mg dose twice a day was too much for me I got really sick but the 5 mg dose twice a day decreases my appetite and makes me a little nauseated and dizzy but so far that is the only things negative that have happened to me.

3:12 AM  
Blogger Wallace Obese Looser said...

This comment has been removed by a blog administrator.

11:44 PM  
Blogger Boni said...

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12:03 AM  
Blogger Mike Hussey said...

Diabetic retinopathy could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to a new research.

10:19 AM  
Blogger Susan said...

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2:38 PM  
Anonymous F. Belt said...

Change your lifestyle. If you’re calling this a “diet,” then you’re going to gain all the weight back (and more) within a few months of losing it. Diets do not work. Diets are temporary. When you change your dietary lifestyle, however, you’re changing your habits – and you’re putting yourself on track for long-term / continued success and weight maintenance. Don’t ever tell anybody you’re on a diet – ever. I’m speaking from experience, here – a reformed low-carber. Worked out well for a while, but ultimately failed because my entire lifestyle didn’t change (permanently).

8:46 AM  
Anonymous P. Hentermine said...

I used Byetta for about six months as my insulin intake started creeping upward as well as my weight. It was great as I lost the 20 lbs and kept them off. I then went on the pump and used Symlin for two months which did cut down on boluses but seemed to be more trouble and really didn't curtail my food intake as Byetta did...so I'm off of it now...my endo has suggested tyring Byetta again but I'm thinking not at the present time...I want to be free of injections for awhile.

8:13 AM  
Anonymous buy generic viagra online said...

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12:49 AM  
Blogger Herbalife UK said...

Thanks for the weight loss guidance..it is a problem these days to deal with fat in our lives ... I think a corrective way of eating and lifestyle should help. Herbalife Diet

5:03 AM  

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